Which of the following benzodiazepines shows the potential for “rebound insomnia
ID: 215003 • Letter: W
Question
Which of the following benzodiazepines shows the potential for “rebound insomnia” after discontinuing long term treatment? Insomnia means that the person cannot go to sleep. There are drugs of abuse called “sedatives” to help alleviate this condition. Select the Best answer for the medicine that, after it is used for sleep for a long time, the person then cannot go back to sleep again and the condition persists and the condition actually gets worse.
Triazolam
Flurazepam
Temazepam
Diazepam
A.Triazolam
B.Flurazepam
C.Temazepam
D.Diazepam
Explanation / Answer
Answer:
Which of the following benzodiazepines shows the potential for “rebound insomnia” after discontinuing long term treatment?
A) Triazolam - Potential rebound insomnia, therefore it is is indicated for the short-term treatment of insomnia that is generally 7-10 days
B) Flurazepam
C) Temazepam - Potential rebound insomnia (short half life and fast onset of action)
D) Diazepam
Explanation: The rebound insomnia is attributed to the short and intermediate half-lives of these drugs. Diazepam and flurazepam benzodiazapenes have longer half-lives and are therefore usually donot cause rebound insomnia on withdrawal symptoms.
Half Life:
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