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2. (8 points) Short answers to questions: a. Please match the characteristics of

ID: 215207 • Letter: 2

Question

2. (8 points) Short answers to questions: a. Please match the characteristics of Euchromatin vs. Heterochromotin: Open chromatin Darkly stained Silenced Active Highly methylated b. Please match the characteristics of Histone code vs. DNA (genetic) code: Changes in the code are inherited permanently: Changes in the code are reversible: What kind of code is H3K27Me3? What does it signify? What kind of code (active or repressive) is acetylated H3K9? Why? c. Telomerase is involved in DNA replication. What is the template this enzyme use? What is the function of this enzvme? Who discovered this enzyme? Why studying this enzyme is relevant to aging and cancer?

Explanation / Answer

Q. a: Answer: Euchromatin - Open and Active

Heterochromatin - Darkly stained, silenced and highly methylated

Q. b: Answer: Histone Code – change in the code are reversible

                        DNA (Genetic) Code – Change in the code are inherited permanently

H3 – H3 Histone family

K – Standard abbreviation for Lysine

27 – Position of amino acid at N-terminus

Me – Methyl group

3 – Number of methyl groups added to H3 proteins

Q. c: Answer:

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