Compared to an RBC with intracellular osmolarity and toni and 10 mM Glycerol is

Question

Compared to an RBC with intracellular osmolarity and toni and 10 mM Glycerol is (assume perfect dissociation of NaC) city of 280 mOsm, an extracellular solution of 140 mM Naci Select one: O a. Hyper-osmotic and iso-tonic, and will have no effect on RBC volume O b. Hyper-osmotic and Iso-tonic, and will cause crenation of RBCS C. Hyper-osmotic and Iso-tonic, and will cause lysis of RBCs O d. Hyper-osmotic and Hypo-tonic, and will cause lysis of RBCs e. Iso-osmotic and Hypo-tonic, and will cause lysis of RBCs

Explanation / Answer

The total osmolarity of 140 mM NaCl, 10 mM glycerol solution = [2 x (NaCl concentration)] + [1 x (Glycerol concentration)] = 2(140) + 1(10) = 280+10 = 290 mOsm.

NaCl dissociates into two particles Na+ and Cl- so each mole of NaCl will have 2 osmoles while for each mole of glycerol there will be one osmole.

So it will be hyperosmotic to RBC. Also, tonic it depends on water content not on the solute, it will be isotonic.

Glycerol can slowly penetrate RBC membrane, thus it Initially will behave as solute (NaCl) but disappears (0 osmolarity).

Because of very less difference in osmolarities, there will not be any effect on RBC volume.

Final Answer: Hyper-osmotic and isotonic, and will have no effect on RBC volume.

Related Questions

Navigate

• Browse (All)
• Browse C
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.