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Gene A codes for a liver enzyme and has two alleles; A1 and A2. A1A1 individuals

ID: 215660 • Letter: G

Question

Gene A codes for a liver enzyme and has two alleles; A1 and A2. A1A1 individuals are normal, and produce 500 units of the functional enzyme. Allele A2 is the result of a point mutation that changed the start codon to ACG. Based on this information:

A2A2 individuals produce normal amounts of a dysfunctional enzyme

A2A2 individuals produce lesser amounts of the functional enzyme.

A1A2 individuals produce 250 units of the functional enzyme.

A2A2 individuals produce no enzyme at all.

Two of the above

A.

A2A2 individuals produce normal amounts of a dysfunctional enzyme

B.

A2A2 individuals produce lesser amounts of the functional enzyme.

C.

A1A2 individuals produce 250 units of the functional enzyme.

D.

A2A2 individuals produce no enzyme at all.

E.

Two of the above

Explanation / Answer

The correct answer should be E) two of the above

Those two are D and C as there is a mutation in start codon, so there will be no production of enzyme in case of A2 whatsoever. Hence, a1a2 would produce half of a1a1 protein and a2a2 would not be abe to form any protein,

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