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1. In a recent seminar, Dr. Anna Salazar presented on a set of experiments in wh

ID: 216060 • Letter: 1

Question

1. In a recent seminar, Dr. Anna Salazar presented on a set of experiments in which she fed flies food with blue food coloring. Healthy flies looked normal, while unhealthy flies would take on a blue color throughout their bodies (the "Smurf" phenotype). She hypothesized that this was due to defects in one type of protein we have discussed in Block 2 A. (2pts) In the "Smurf flies, what kind of tissue does the blue food coloring first cross to get into the body? B. (4pts) Which type of protein in this tissue do you think is affected in "Smurt" flies, and how could a mutation change its molecular & cellular function to cause the "Smurf" phenotype? C. (4pts) How could the mutation in Part B lead to overall poorer health of the organism?

Explanation / Answer

A. Intestinal tissue does the blue food coloring first cross to get into the body.

B. Hemolymph is the protein affected. Mutation that resulted in the increased absorbance of blue dye and resulted in the smurf phenotype.

C. Energy metabolism increases the activity of intestine and hence, in this way lifespan of flies increased.