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Which of the following is true about second O They produce their effect by chang

ID: 216062 • Letter: W

Question

Which of the following is true about second O They produce their effect by changing in cAMP is an example of a second messenger. They are proteins O They are enzymes D Question 2 1 pts Which of the following would eventually lead to signaling being turned ON? OG protein uses its GTPase activity O Tyrosine kinase receptors dimerize O G protein binds to GPCR O G protein is bound to GDP O Tyrosines are dephosphorylated on tyrosine kinase receptors Question 3 1 pts Which of the following can lead to a change in shape and thus a change in activity? OA phosphatase removes a phosphate from a protein O A protein kinase gets phosphorylated O A ligand binds a receptor O cAMP binds a protein kinase O G protein hydrolyzes GTP

Explanation / Answer

Answer to the first question

Which of the following is true about second messengers?

They produce their effect by changing in concentrations (Reason: Second messengers activate various cyclin kinases leading to a cascade of reactions. This, in turn, increases the strength of the original messenger)

cAMP is an example of second messenger (Reason: Epinephrine triggers the release of cAMP which acts as a secondary messenger and helps in the conversion of glycogen to glucose in the liver)

Answer to question 2

Which of the following would eventually lead to signaling being turned on?

Tyrosine kinase receptor dimerize. (Reason: Ligands bind to these receptors and dimerize them. This release tyrosine which undergoes trans-phosphorylation leading to a signal cascade in the plasma membrane)

Answer to question 3

Which of the following can lead to a change in shape and thus a change in activity?

A ligand binds a receptor (Reason: The binding of a ligand to a receptor causes a conformational change of the receptor. This process is called receptor activation)

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