Hardy-Weinberg genotype frequencies are calculated as expectations under the ass
ID: 21632 • Letter: H
Question
Hardy-Weinberg genotype frequencies are calculated as expectations under the assumptions required for a formal mathematical proof of the H-W equilibrium law. Violations of the assumptions are detected by comparing expected and observed genotype frequencies. The genotype frequencies over five generations recorded above do not show perfect concordance between expected and observed values. The departures from expectation are, most likely, the result of mutation drift selection nonrandom mating phlebotomyExplanation / Answer
mutation
evolutionary force mutation lead to change in gene frequency of allele A1 AND A2
A1 A1 ,A1A2; A2A2
A1= 0.5
A2=0.5
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A1 A1 ,A1A2; A2A2
0.26---------0.51--------0.24
A1= 0.26+ 0.51/2= 0.26 +0.255 =A1= 0.515
A2= 0.24+ 0.51/2= 0.24 +0.255 =A1= 0.495
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