Naive B cells can become activated with or without the assistance of helper T ce
ID: 216587 • Letter: N
Question
Naive B cells can become activated with or without the assistance of helper T cells. Identify which steps occur when T cells are not part of the process (the T-cell-independent route) and which steps are important for the activation process that includes the T cells. Some of the steps will occur no matter which method of activation is used.
Which of the following steps occur in T-cell-independent B-cell activation?
Choose one or more:
A.
Antigens processed by the cell are displayed on the surface of the B cell in MHC II receptors.
B.
Antigens with multiple repeating epitopes cross-link two B-cell receptors on the membrane of the B cell.
C.
The B cell produces unique receptors that bind to antigen.
D.
A process called "capping" initiates a signal cascade that activates the B cell.
E.
Antigens bound to the B-cell receptors are endocytosed and degraded by the cell.
F.
The B cell proliferates and differentiates into plasma cells and memory cells.
G.
T cells bind to the antigen and stimulate activation of the B cell.
Which of the following steps occurs when a helper T cell activates a naive B cell?
Choose one or more:
A.
Antigens with multiple repeating epitopes cross-link the two receptors on the membrane of the B cell.
B.
The B cell produces unique receptors that bind to antigen.
C.
A T cell binds to the antigen displayed by the B cell and stimulates the activation of the B cell.
D.
Antigens bound to the B-cell receptors are endocytosed and degraded by the cell.
E.
Antigens processed by the cell are displayed on the surface of the cell in MHC II receptors.
F.
A process called "capping" initiates a signal cascade that activates the B cell.
G.
The B cell proliferates and differentiates into plasma cells and memory cells.
A.
Antigens processed by the cell are displayed on the surface of the B cell in MHC II receptors.
B.
Antigens with multiple repeating epitopes cross-link two B-cell receptors on the membrane of the B cell.
C.
The B cell produces unique receptors that bind to antigen.
D.
A process called "capping" initiates a signal cascade that activates the B cell.
E.
Antigens bound to the B-cell receptors are endocytosed and degraded by the cell.
F.
The B cell proliferates and differentiates into plasma cells and memory cells.
G.
T cells bind to the antigen and stimulate activation of the B cell.
Explanation / Answer
Which of the following steps occur in T-cell-independent B-cell activation?
Choose one or more:
A.
Antigens processed by the cell are displayed on the surface of the B cell in MHC II receptors.
B.
Antigens with multiple repeating epitopes cross-link two B-cell receptors on the membrane of the B cell.
C.
The B cell produces unique receptors that bind to antigen.
D.
A process called "capping" initiates a signal cascade that activates the B cell.
E.
Antigens bound to the B-cell receptors are endocytosed and degraded by the cell.
F.
The B cell proliferates and differentiates into plasma cells and memory cells.
G.
T cells bind to the antigen and stimulate activation of the B cell.
Which of the following steps occurs when a helper T cell activates a naive B cell?
Choose one or more:
A.
Antigens with multiple repeating epitopes cross-link the two receptors on the membrane of the B cell.
B.
The B cell produces unique receptors that bind to antigen.
C.
A T cell binds to the antigen displayed by the B cell and stimulates the activation of the B cell.
D.
Antigens bound to the B-cell receptors are endocytosed and degraded by the cell.
E.
Antigens processed by the cell are displayed on the surface of the cell in MHC II receptors.
F.
A process called "capping" initiates a signal cascade that activates the B cell.
G.
The B cell proliferates and differentiates into plasma cells and memory cells.
There are two ways of B cell activation. B cells are activated by T cells and independent of T cells.
In B cell activation independent of T cell activation following steps are initiated:-
B cells produce antigen binding receptors. These receptors with anitgen are processed and it further develops into plasma cells and memory cells.
In T cell dependent pathway antigens are processed and displayed on the cell surface. Then B cells are activated by T cells.
A.
Antigens processed by the cell are displayed on the surface of the B cell in MHC II receptors.
B.
Antigens with multiple repeating epitopes cross-link two B-cell receptors on the membrane of the B cell.
C.
The B cell produces unique receptors that bind to antigen.
D.
A process called "capping" initiates a signal cascade that activates the B cell.
E.
Antigens bound to the B-cell receptors are endocytosed and degraded by the cell.
F.
The B cell proliferates and differentiates into plasma cells and memory cells.
G.
T cells bind to the antigen and stimulate activation of the B cell.
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