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Purpose: The purpose of this paper is to get cancer cells to survive under metab

ID: 216700 • Letter: P

Question

Purpose: The purpose of this paper is to get cancer cells to survive under metabolic stress by Snail regulating glucose flux in direction to PPP The major questions: Does Snail-PFKP axis contributes to an important regulatory part in aerobic glycolysis. Hypothesis: They hypothesize that by adjusting the metabolism, will overpower oxidative stress throughout the progression of cancer Results/Interpretations: Snail regulates glucose flux toward PPP, which allows cancer cell to survive while under metabolic stress. Figure 3 1. What is the question the authors are asking (for that specific part of the figure)? 2. How is the question answered? What is the method/technique? (You only have to state it, with a brief explanation of the method.. .no detailed step by step information needed.) 3. What is the answer to the question? (Explanation of results) d. Explain how the data is represente Explain the use of controls in the experiment. 4. What is the interpretation of the figure? What does 5. How does the data support or falsify the overall 6. What is the next step the authors propose? Do you the data mean? hypothesis of the paper? agree with that step?

Explanation / Answer

The question that is asked in here is if when the cancer cell is starved during intense metabolism since they are immortal cells. During this condition hypoxia is induced and the cell should eventually die but does happen with cancer cells, so does snail has anything to do with the survival of these cancer cells.

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