If mammalian cells receive a go-ahead signal at the G1 checkpoint, they 28) will

Question

If mammalian cells receive a go-ahead signal at the G1 checkpoint, they 28) will A) move directly into telophase. B) complete the cycle and divide. C) exit the cycle and switch to a nondividing state. D) show a drop in MPF concentration. The "restriction point" occurs here: A) M B) G1 C) S D) G2 Cells from an advanced malignant tumor most often have very abnormal chromosomes, and often an abnormal total number of chromosomes. 29) 30) Why might this occur? A) Cancer cells are no longer density-dependent. B) Cancer cells are no longer anchorage-dependent. C) Chromosomally abnormal cells can still go through cell cycle checkpoints. D) Chromosomally abnormal cells still have normal metabolism.

Explanation / Answer

28) Option B is correct. If mammalian cells receive a go-ahead signal at the G1 checkpoint, they will complete the cycle and divide.

29) Option B is correct. The "restriction point" occurs at G1 phase.

30) Option C is correct. Cells from an advanced malignant tumor most often have very abnormal chromosomes, and often an abnormal total number of chromosomes. This occurs because chromosomally abnormal cells can still go through cell cycle checkpoints.

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