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1) If two loci show a 50% recombination frequency in a two-point test cross, wha

ID: 217214 • Letter: 1

Question

1) If two loci show a 50% recombination frequency in a two-point test cross, what would happen?

2) What would you expect to have happened if Mendel had worked with only partially linked genes?

3) What would happen if crossing over took place before mitosis as well?

4) In a dihybrid cross between two totally unlinked loci (with full penetrance, expressivity and dominance in each) we expect a 9:3:3:1 phenotypic distribution. What distributions could you expect from a dihybrid between fully linked loci?

5) what is the likely outcome of a dihybrid between partly linked genes?

Thank you

Explanation / Answer

1. if two local have 50% recombination frequency then they give rise 50% recombinent offsprings. The remaining 50% offsprings are same as parental in genotypes.

In other points it is also clear that to loci are 50 minute uparts from each other. Because 1% recombination means genes are 1 map unit aparts.

2. If mendal use to do work on partially linked gene than he wil not able to give the idea about law of Independent assortment, law of dominance and law of segregation.

Becasue these conditions are only applicable for diploid cells with non linkage.

3. crossing over before mitosis leads to improper division of cells. distribution of chromosomes and genes also abnormal.

4. When two things are totally unlinked then the ratio will not deviate from mendallian ratio.