You are investigating the control of gene expression of vestigial, a gene that i

Question

You are investigating the control of gene expression of vestigial, a gene that is normally expressed in the imaginal dises that will become wings in Drososophila. The following table characterizes the expression pattern of the vestigial gene in six homozy gous mutants that were identified in a screen for flies with abnormal wing formation. Characterization of vestigial gene expression was also done orn progeny from crosses of homozygous mutants to the wild type, creating heterozygotes. The gene is normally expressed in the imaginal discs but not in the thorax region. Remember that gene dosage- or amount of gene product- is proportional to the number of functional copies of a gene. 2. relative mRNA levels imaginal dise thorax imaginal disc thorax Strain 100% 0% 5% 100% 5% 10090 100% 50% 100% 100% 100% 5% 0% 5% 100% 5% 5% 100% 5% 5% 5% 50% 100% 0% 1% 100% 190 0% 100% 50% 100% 100% 100% 196 0% 190 100% 19 0% 100% 1% 1% 1% 50% Wildtype (control) Mutant 1 Mutant 2 Mutant 3 Mutant 4 Mutant 5 Mutant 6 Mutant 2 x wild type Mutant 3 x wild type | Mutant 4 x wild type l Mutant 6x wild type n the information above, match the mutant strain on the left with the type of genetic alteration listed on the right. Each of the six mutations is one and only one of the genetic mutants listed. (0.4 pts each, 24 pts total) a. missense mutation in the vestigial gene b. mutation in the promoter c. mutation in a silencer d. defective repressor gene e. mutation in an enhancer f. defective activator gene Mutant :_ Mutant 2:_ Mutant 3 Mutant 4:_ Mutant 5:_ Mutant 6:_

Explanation / Answer

Answer':-

Mutant 1 - mutation in promotor

Mutant 2 - mutation in an enhancer

Mutant 3- defective activator gene

Mutant 4- defective repressor gene

Mutant 5- missense mutation in vestigeal gene

Mutant 6- mutation in silensor

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