Problem 2 In cats, there is a coat color gene located on the X chromosome. This

Question

Problem 2 In cats, there is a coat color gene located on the X chromosome. This gene has two alleles. The dominant allele codes for a protein that results in orange hair and it is incompletely dominant to the recessive allele that codes for black hair The heterozygote has tortoise shell color hair (a mix of orange and black). Show your work! a) State the phenotypes that are possible and the probability of having an offspring with each phenotype for a cross between a black female and an orange male b) The length of cat hair is controlled by one g ene with two alleles. The S allele codes for short hair and the s allele codes for long hair. Using the information on coat color from problem "a", state the phenotypes that are possible and the probability of having an offspring with each phenotype for a cross between a long-haired black female and a heterozygous short-haired orange male. Cats have a gene known as the white masking gene, which has two alleles and is also found on the X chromosome. The W allele produces a protein that prevents the production of pigment producing cells. The w allele produces a protein that results in normal production of pigment producing cells. The WW and Ww genotypes produce white cats no matter what other color genes they carry. Only cats with only the w allele will express their normal pigmentation. Using the info from "a" and "b", determine the possible phenotypes and the probability of having an offspring with each genotype and phenotype for a cross between a cat that has the genotype XBwXbwSs and a cat with the genotype XbwYSs What are the phenotypes of these two cats (XBWXwSs ndbwYSs) Calculate the phenotypic and genotypic frequencies under: . the hypothesis of complete linkage and u. also under the hypothesis of independent assortment e between the white masking gene and the coat color gene is 10 cM. How many offspring of each phenotype do you expect to observe if these two cats produce 10 litters of 10 cats each?

Explanation / Answer

a) Orange colour dominant Xo

Black colour recessive Xb Xb

Shel colour Xo Xb

Black female x orange male

Xb Xb x Xo Y

Offspring : Xb Xo, Xb Y, Xb Xo, Xb Y

Xb Xo : shel colour female with probability 2/4

Xb Y : black colour male with probability 2/4

b) short hair S

Long hair s

Long hair black female x heterozygous short hair orange male

ss XbXb x Ss Xo Y

SsXb Xo short hair black shell colour female 1/4

ss Xb Xo long hair shell colour female 1/4

ss Xb Y long hair black male 1/4

Ss Xb Y short hair black male 1/4

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