instructions INFECTIOUS DISEASE CASE STUDY 22 Sucty nne-year old Carl Landon has
ID: 217657 • Letter: I
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instructions INFECTIOUS DISEASE CASE STUDY 22 Sucty nne-year old Carl Landon has suffered from asymmetrical flaccid paralysis since childhood. That is, he has weak, paralysis on one leg as a result of an infection common to children in the early 1900's. Typical infections could range from droopy mald feyer and headache to temporary stiff neck and back and most sernously, muscle paralysis. The most debilitating effect resulted in paralysis of the respiratory muscles, requiring use of the iron lung machine. Following infection, Carl suffered from nearly complete paralysis of both lower limbs. For the next sixth months Carefiul arrention to exercises preserbed by his doctor and use of er braces alowed some recovery However as is usually the case after sat months, no further improvement was seen, and Carl remained in his present condition. Laboratory Diagnosis Due to rourune immunization, this infection is rarely seetn in the United States buz does occur in Mexico and other ton in these areas or brought into the ui S can be obrained by a fourfold or greater neutralizing antibody titer chanse between paired acute (IS 21 day) and convalescent (2S day) senum samples PleNot swed Ths test can only be taken once AntempS Fürde Completion This test car be saved and reaumed aterExplanation / Answer
4. A. The current recommendation for immunization in the united states is IPV.
IPV, used in the U.S. since 2000, is given as an 4 injections in the leg or arm, depending on age.
OPV is used in other parts of the world.
5. Yes, still we consider to give vaccine in the US. Because 1 in million of people the vaccine becomes ill. There genome is not adapt to the vaccine. So due to one individual or rare event occurs we no need to stop the vaccination.
1. Polio
2. Ingestion of water contaminated with feces
3.
Multiplication of virus in throat and small intestine
Virus invades tonsils and lymph nodes
Viremia as virus enters the blood
Entrance of virus in CNS through penetration of capillary walls
Virus multiplies in cytoplasm of motor nerve cells result in cell death
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