1) Match the regulatory ncRNA to its target. Please help, the answers I put said

Question

1) Match the regulatory ncRNA to its target.

Please help, the answers I put said that I got 1 wrong but I'm not sure which one...

SER3

Please help verfiy if my answers are correct or not. Thank you!

2) Which class of non-coding RNAs plays a role in imprinting?

piRNA

miRNA

lincRNA?

rRNA

3) Which of the following is NOT a mechanism by which miRNAs can inhibit gene expression?

by blocking elongation of translation

by competing with elF4E for mRNA cap binding

by facilitating mRNA polyadenylation?

by triggering co-translational protein degradtion

Regulatory ncRNA Target Choices My Answer SRG1

SER3

SER3 HOTAIR HOX-D or HOX-C HOX-C AIR Igf2r or Igf2 Igf2r Tsix lin14 Xist lin4 PHO84 lin14

Explanation / Answer

ANS.1) a)SRG1 is require for siliencing of SER3 in the gene regulation.

b)HOTAIR is encoded within the HOX-C but it requires for the siliencing of the HOX-D in gene regulation process.

c)AIR is targeted for siliencing of the igf2r in gene reugulation

d)Tsix requires for the deletion of Xist.

e)lin4 protein coding target is lin14.

ANS. 2)MiRNA plays a role in impriting.it is epigenetic phenomena that causes genes to be expressed in a parent-of-origin-specific manner.

ANS. 3)By triggering co-translational protein degradation is not the mechanism by which miRNAs can inhibit gene expression. the mechanisms which involves in inhibiting of gene expression is by blocking elogation of translation,by competing with elF4E for miRNA cap binding and by facilitating mRNA polyadenylation.

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