18. The mechanism for all template-directed synthesis of any type of nucleic aci

Question

18. The mechanism for all template-directed synthesis of any type of nucleic acid involves the following C2 a) Nucleophilic attack of a 3 OH toward a S phosphate of an incoming nucleoside triphosphate points) b) Nucleophilic attack of a 5' OH toward a 3' phosphate of an incoming nucleoside triphosphate hate of an incoming nucleoside triphosphate d) Nucleophilic attack of a 5' OH toward a 5' phosphate of an incoming nucleoside triphosphate ?-c) Nucleophilic attack of a 3, OH toward a 3, phosp e) More than one of these would work, since the mechanism is not universal

Explanation / Answer

The mechanism for all template-directed synthesis of any type of nucleic acid involves the following
A) Nucleophilic attack of a 3' OH toward a 5’ phosphate of an incoming nucleoside triphosphate.

The following activity of DNA Pol I is responsible for filling in or patching:

A) 3’ to 5’ exonuclease

This is a proofreading process.

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