Which outline of a reaction sequence leading to the conversion of aspartate to c

Question

Which outline of a reaction sequence leading to the conversion of aspartate to carbondioxide is correct? (all start with aspartate) A) 1. Transamination to alpha-ketoglutarate 2. alpha-ketoglutarate oxidation in the citric acid cycle to malate . Malate conversion to pyruvate by malic enzyme 4. Pyruvate oxidation to acetyl-CoA by pyruvate dehydrogenase 5. Oxidation of acetyl-CoA in the citric acid cycle B) Aspartate cannot be oxidized to carbondioxide C) D) 1. Transamination to oxaloacetate 2. Two rounds of the citric acid cycle fully convert oxaloacetate to carbondioxide 1. Transamination to oxaloacetate 2. Oxaloacetate conversion to malate then to pyruvate through malate dehydrogenase and malic enzyme . Pyruvate oxidation to acetyl-CoA by pyruvate dehydrogenase 4. Oxidation of acetyl-CoA in the citric acid cycle E) 1. Transamination to oxaloacetate 2. Oxaloacetate conversion to citrate in the citric acid cycle. 3. Citrate conversion to acetyl-CoA by citrate lyase 4. Oxidation of acetyl-CoA in the citric acid cycle

Explanation / Answer

Which outline of a reaction sequence leading to the conversion of aspertate to carbondioxide is correct?

D) 1) Transamination to oxaloacetate

2) Oxaloacetate conversion to malate then to pyruvate through malate dehydrogenase and malic enzyme

3) Pyruvate oxidation to acetyl-CoA by pyruvate dehydrogenase

4) Oxidation of acetyl-CoA in the citric acid cycle

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