QUESTION 1 10 points Saved Which of the following is false regarding the role of

Question

QUESTION 1 10 points Saved Which of the following is false regarding the role of complement in the nervous system? Complement tugs synapses for removal by microglia Complement has no effect on adult neurons Knockout of complement proteins impairs the ocular dominance process in the LGN O Astrocyte signaling is necessary for complement upregulation in neurons QUESTION 2 10 points Saved What is the function of the rostral migratory stream? To move newly born cells from the SGZ to the hippocampus To move newly born cells from the fourth ventricle to the cerebellum To move old, apoptotic cells from the hippocampus to the SVZ O To move newly born cells from the SVZ to the olfactory bulb

Explanation / Answer

1. Ans.-- Complement has no effect on adult neurons

Reason-- Complement makes the neuronal stem cells differentiate and migrate to prevent injury and death in adult cells due to toxic agents.

2. Ans-- To move newly born cells from the SVZ [subventricular zone ] to the olfactory bulb

Reason -- The migration of newly generated neuroblasts begins at the lateral ventricle , continues along the RMS and terminates in the OB , where mature interneuron populations are generated. Astrocytes ensheath the migrating neuroblasts and are thought to restrict and contain the neuroblasts to their specific pathway.

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