James has 8 siblings, 5 brothers and 3 sisters. All his siblings and himself are

Question

James has 8 siblings, 5 brothers and 3 sisters. All his siblings and himself are suffering from symptoms related to eyes, some even have complete paralysis of eye muscles. James was told that they have a genetic disorder that runs in the family. James' fater is healthy: about mother he does not know - she died at her early 40th. James'sister, Susan, is expecting a child. Her husband does no have symptoms of the disease. What is the probability that Susan's child will be healthy? Select one: a. 0% b. 25% c. 50% d. 100% e. Need more information

Explanation / Answer

The correct answer is Option C that is 50%. The inheritance pattern is X linked dominant. The father is healthy but all children are affected that means the mother was affected. Genotype of her mother is XCXC. The Genotypic Susan is XCX and she is affected too. Her husband is healthy and hence genotype is XY. So, from this the possible genotype of their child is XY, XX, XCX and XCY. So, probability is 2/4 that is 50%.

Hence option C is the correct answer.

Related Questions

Navigate

• Browse (All)
• Browse J
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.