Write 13 Conceptual Multiple Choice Questions and Included Your Answer Key for T
ID: 219595 • Letter: W
Question
Write 13 Conceptual Multiple Choice Questions and Included Your Answer Key for Two Pictures Below binding domain Receptors Enzyme-linked receptors Cell surface receptors Enzyme-linked Cytosol G-protein-coupled Ligand-gated ion channels atilyie domainSignal binding causes conformational hange which activates atalytic domain (a) Structure of enzyme-linked receptors Hormone Receptor Signal- Most are protein kinases receptor + ADP The binding of a hormone to a receptor causes a conformational change in the receptor, resulting Signaling molecule binds and activates the catalytic function of the receptor Phosphorylated CytosolExplanation / Answer
1. From the following, which hormone does not have cell surface receptors?
a) Growth Hormone b) Adrenaline c) Thyroxine d) Insulin [answer: c]
2. Which of the following statement is not correct about cyclin-dependent protein kinases?
a) Their activity fluctuates during the cell cycle. b) Each type of cell contains one specific form. c) The activity is regulated by cyclins. d) None of these. [answer: a]
3. Which of the following protein kinase controls the passage of a cell through stages of a cell cycle?
a) Cyclins b) Tyrosine kinase c) Cdk activating kinase d) Cyclin-dependent kinase [answer: d]
4. Which enzyme is activated by cAMP that passes on a hormonal signal?
a) Protein kinase B b) Protein kinase C c) Protein kinase A d) G protein receptor kinase [answer: c]
5. From the following, SH2 domain binds specifically to?
a) Ca+2 b)Phosphorylated tyrosine residue c) Phosphorylated serine residues d) GDP [answer: b]
6. Which of the following is/are phosphorylated to activate the protein kinase ERK?
a) Both Tyr and Thr b) Only Thr c) Only Tyr d) Only Ser [answer: a]
7. cGMP- dependent protein kinase is also called as?
a) Protein kinase A b) Protein kinase G c) Protein kinase B d) Protein kinase C [answer: b]
8. Which of the following is produced by the activation of guanylyl cyclase?
a) Guanosine 2', 5'-cyclic monophosphate b) Guanosine 1',5'-cyclic monophosphate c) Guanosine 3',5'-cyclic monophosphate d) Guanosine 4',5'-cyclic monophosphate [answer: c]
9. Which of the following is not a type of signaling molecule?
a) Thyroxine b) Insulin c) Testosterone d) Adenylate cyclase [answer: d]
10. Which of the following comes under the category of cell surface receptors?
a) G protein-linked receptors b) Enzyme-linked receptors c) Ion-channel linked receptors d) All of these [answer: d]
11. Which of the following statement is wrong about G proteins?
a) They must be active before the cell can make cAMP b) They become activated when bound to GDP c) They are involved signal cascade d) They bind to and are regulated by guanine nucleotide [answer: b]
12. In paracrine signaling, the signaling molecules affect only?
a) target cells close to the cell from which it was secreted b) target cells distant from its site of synthesis in cells c) Both (a) and (b) d) None of these [answer: a]
13. Which of the following describes Ras protein?
a) Serine-Threonine kinase b) Tyrosine kinase c) Small monomeric GTPase switch protein d) G-protein switch [answer: c]
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