. Verizon LTE * 91% 11:16 AM a mymasonportal.gmu.edu Home ? Upload Assignment: A

Question

. Verizon LTE * 91% 11:16 AM a mymasonportal.gmu.edu Home ? Upload Assignment: Assignment 4 ASSIGNMENT INFORMATION Due Date: (Use EST/EDT time) Sunday, April 1, 2018 11:59 PM Points Possi 5 You have developed a transgenic mouse that is characterized by a large, bulbous corpus callosum. The mouse's corpus callosum is abnormally thick and has made axons crossing back and forth across the midline Given what you know about chemoattractants and repellents, what might have happened to this mouse's genome to cause it to have abnormal corpus callosum thickness? Your answer shouldn't be more than a few sentences When finished, make sure to click Submit Optionally, click Save as Draft to save changes and continue working later, or click Cancel to quit without saving changes Cancel Save Draft Submit

Explanation / Answer

Netrin 1 is a chemoattractant that is found to disturb the genes that are responsible for the normal development of corpus callosum. Monocyte chemoattractant protein 1 and certain cyokines are also the reason of causing abnormal corpus callosum thickness. The thick corpus callosum disturb the normal signaling of neurons.

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