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1) In which direction does RNA polymerase move along the template strand? a) 3’-

ID: 219865 • Letter: 1

Question

1) In which direction does RNA polymerase move along the template strand?

a) 3’-5’

b) 5’-3’

c) Both

d) None of the above

2) Techniques to identify new peptide drugs include: (multiple answers)

a) peptide libraries

b) bioinformatics

c) aptamer library screening

d) phage display libraries

3)

Technosphere was so successful delivering insulin, GlaxcoSmithKline decides to use it to deliver their new peptide drug for asthma. However, they find that the amount of bioactive drug delivered is so low that Technospheres are not going to work. Why?

a. The peptide is primarily deposited in the trachea

b. The peptide is degraded under the pH conditions necessary to release it from the technosphere

c. The pMDI used for delivery requires the patient to coordinate actuation and inspiration

d. None of the above

Explanation / Answer

1) In which direction does RNA polymerase move along the template strand?
a) 3’-5’
b) 5’-3’
c) Both
d) None of the above

The answer is a) 3'-5'.

As the RNA polymerase synthesizes RNA molecules form 5'-3' direction as it is moving on the 3'>5' direction. So, the answer is a) 3’-5’.

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