aria is a life-threatening illness caused by Plasmodium parasites that are trans

Question

aria is a life-threatening illness caused by Plasmodium parasites that are transmitted to humans by infected Anopheles mosquitoes, Freitas-Junior et al. (2005) describe how multiple Plasmodium species evade host immune systems via antigenic variation, wherein the parasites regularly change the antigens on their surfaces to evade detection by host immune cells. The mechanism that varies antigen expression is epigenetic: histone proteins associated with a suite of antigen-coding genes are repeatedly chemically modified, such that chromatin structure changes over time, producing variation in expression of particular antigen-coding genes. What chemical changes in histone proteins are responsible for changes in gene expression? addition or removal of methyl and acetyl groups within the tail domains of histones proteolytic cleavage of the globular and tail domains of histone proteins into oligopeptides removal of electrically-charged functional groups from the tail domains of histones addition of acidic groups and removal of alkaline groups within the tail domains of histones addition or removal of methyl and acetyl groups within the globular domains of histones

Explanation / Answer

the addition or removal of methyl and acetyl groups within the tail domains of histones are responsible for cganges in gene expressions that is trimethylation of H3 lysine 27, dri and tri-methylation of H3 lysine 9 etc.

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