Most eukaryotic ABC transporters are involved in exporting small molecules from

Question

Most eukaryotic ABC transporters are involved in exporting small molecules from the cytosol. In this subset of the ABC transporters, does the small molecule bind better to the ATP-bound (B) or the ATP- free (F) transporter? Write down your answer as B or F. Hint: The ATP-bound transporter “faces outward.” Most eukaryotic ABC transporters are involved in exporting small molecules from the cytosol. In this subset of the ABC transporters, does the small molecule bind better to the ATP-bound (B) or the ATP- free (F) transporter? Write down your answer as B or F. Hint: The ATP-bound transporter “faces outward.” Most eukaryotic ABC transporters are involved in exporting small molecules from the cytosol. In this subset of the ABC transporters, does the small molecule bind better to the ATP-bound (B) or the ATP- free (F) transporter? Write down your answer as B or F. Hint: The ATP-bound transporter “faces outward.”

Explanation / Answer

ATP -Bound (B)- ATP - Bound since it faces outwards so it has higher binding affinity to the substrates.

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