Choose true or false for the following statements. 1. Steroid hormones are synth

Question

Choose true or false for the following statements.
1. Steroid hormones are synthesized in the same cells where they function. TrueFalse
2. Estrogen is a gonadocorticoid. TrueFalse
3. Glucocorticoid receptors are membrane bound. TrueFalse
4. Glucocorticoid receptors have a nuclear localization signal that is hidden until a glucocorticoid is bound. TrueFalse
5. Two glucocorticoid receptors function as a homodimer. TrueFalse
6. Glucocorticoid receptors bind to GRE elements which are present on newly synthesized mRNAs. TrueFalse

Explanation / Answer

1. Steroid hormones are synthesized in the same cells where they function. False

They have function elsewhere

2. Estrogen is a gonadocorticoid. True
3. Glucocorticoid receptors are membrane bound. False

(they are cytosolic)

4. Glucocorticoid receptors have a nuclear localization signal that is hidden until a glucocorticoid is bound. True

5. Two glucocorticoid receptors function as a homodimer. True

6. Glucocorticoid receptors bind to GRE elements which are present on newly synthesized mRNAs. False

The glucocorticoid response element (GRE) is found in a number of different target genes (DNA) that respond to binding of glucocorticoid.

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