Which of the following statements about the oxidative decarboxylation of pyruvat

Question

Which of the following statements about the oxidative decarboxylation of pyruvate under aerobic conditions in animal cells is correct? The methyl group is eliminated as CO_2 The process is considered as the first catalytic step in the TCA cycle. One of the products of the reactions of the Pyruvate Dehydrogenase Complex is Acetyl-CoA. The Pyruvate Dehydrogenase Complex uses all of these as cofactors: NAD^+, lipoic acid, pyridioxal phosphate, and FAD. The reaction is so important to energy production that the E1 and E_2 components of Pyruvate Dehydrogenase can be used for the oxidative decarboxylation of a-ketoglutarate.

Explanation / Answer

The correct statements are:

The process is considered as the first catalytic step in the TCA cycle.

One of the products of the reaction of the Pyruvate Dehydrogenase Complex is Acetyl CoA.

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