Which of the following statements about epithelial tumors is true? Tumors of the

ID: 225692 • Letter: W

Question

Which of the following statements about epithelial tumors is true?

Tumors of the epithelium are called sarcomas.

Benign epithelial tumors can’t initiate angiogenesis.

Tumors of the epithelium represent nearly 50% of life-threatening cancers.

Epithelial tumors are considered benign if they are contained on the epithelial side of the basement membrane.

Which of the following is a major challenge for tumor cell survival during early invasion/metastasis?

Detachment from the extracellular matrix can cause death by anoikis.

Growth factors in the circulation can cause apoptosis.

Hydrodynamic shear in the stroma can tear tumor cells apart.

Association with platelets can reduce the viability of tumor cells within the large vessels of the venous system.

In a typical sequence, which of these stages of extravasation occurs last?

Tumor cells break through the capillary basement membrane.

Platelets associate with a cancer cell.

Proteases degrade the microthrombus.

A cancer cell proliferates within the capillary.

Tumors of the epithelium are called sarcomas.

Benign epithelial tumors can’t initiate angiogenesis.

Tumors of the epithelium represent nearly 50% of life-threatening cancers.

Epithelial tumors are considered benign if they are contained on the epithelial side of the basement membrane.

a. Benign epithelial tumors can’t initiate angiogenesis.

b. Hydrodynamic shear in the stroma can tear tumor cells apart.

c. Tumor cells break through the capillary basement membrane.

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