The concentration ([S]) dependence of the initial velocity of transport (JS) of

Question

The concentration ([S]) dependence of the initial velocity of transport (JS) of two organic solutes, X and Y, across a membrane is shown below as a Hanes-Woolf plot. What are the fundamental differences between the likely transport mechanisms of the two solutes? Suppose that ouabain inhibited the transport of solute X but left the transport of solute Y unaffected? What would these results suggest about the mechanism(s) of transport of X and Y?

Which of the following two compounds is most likely to correspond to solute X, which to solute Y at pH 7?

Explanation / Answer

Solute Y must be neutral because it is passing through membrane at constant speed on the other solute x will have some charge and membrane is restricting it to pass through it but aas concentration is increasing membrane is allowing it to pass through it at increasing speed.

From the above explanation it is clear out to 2 given molecules one with no charge is solute y and the other with 2 negative charges and 1 positive charge at pH 7 giving net charge to be negative 1 is solute x.

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