What is the primary factor affecting the quality factor of a cantilever based bi

Question

What is the primary factor affecting the quality factor of a cantilever based biosensor operating in the dynamic mode: 1. (A) The spring constant of the cantilever beam (B) Mass of the cantilever beam (C) Damping of the cantilever beam (D) Frequency at which it is operated at In the static mode operation of a cantilever based biosensor for the detection of small molecules (for example: hybridization between short oligonucleotide strands), deflection in the cantilever beam is produced primarily due to (A) Mass of the molecules accumulated on the cantilever (B) Surface stresses induced on the cantilever surface due to the binding/hybridization (C) Resonant frequency shifts in the cantilever beam (D) Changes in the physical dimensions of the cantilever beam due to accumulation of the additional excess mass. TRUE/FALSE The spring constant of the cantilever beam is affected by the mass it accumulates 3. Say you are a graduate student working in the lab on building and testing a cantilever biosensor that operates in the static mode. Through the latest nanofabrication approaches, you fabricate a highly sophisticated cantilever structure whose bending may be read accurately through electronic means. To test this cantilever structure you just fabricated, you functionalize the cantilever surface by dipping it in appropriate reagents and carrying out the necessary protocols. Finally you begin testing the cantilever sensor with actual test samples containing the analyte molecules of known concentration. To your utter dismay, your cantilever beam, even after sufficient analyte binding on its surface does not deflect at all! In a few words, describe where you may have may have gone wrong in the fabrication steps. 4. words, describe where you ma

Explanation / Answer

According to chegg policy, i have to answer only 1st question

1. Ans-(c)

Due to damping, there is relative frequency change and this change lead to the change in quality factor

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