Print Calculator -a Periodic Table Question 2 of 5 A Sapling Learning Low concen

Question

Print Calculator -a Periodic Table Question 2 of 5 A Sapling Learning Low concentrations of warfarin near the detection limit gave the following dimensionless instrument readings: 196.9, 163.3, 153.9, 165.9, 210.9, 151.7, 214.7, 193.3, 126.3, and 197.1. Ten blanks had a mean reading of 52.7. The slope of the calibration curve is 3.23 x 10° M-1. Estimate the signal and concentration detection limits and the lower limit of quantitation for warfarin. Number gnal Detection Limit: Number 1M Concentration Detection Limit Number Lower Limit of Quantitation:

Explanation / Answer

by using all number calculate mean and standard deviation by using formulas

mean = 177.4   = X

standard deviation = 29.23   = S

signal detection limit = Yblank + 3 S

                                 = 52.7 + 3 x 29.23

                                = 140.4

signal detection limit = 140.4

concentration detection limit = 3S / M

                                            = 3 x 29.23 / 3.23 x 10^9

                                             = 2.72 x 10^-8 M

concentration detection limit = 2.72 x 10^-8 M

lower limit of qunatitation = 10 S / M

                                        = 10 x 29.23 / 3.23 x 10^9

                                        = 9.05 x 10^-8 M

lower limit of qunatitation = 9.05 x 10^-8 M

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