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s-Last-Year-Review-Questions (1) Microsoft PowerPoint llA Text Direction Align T

ID: 2306163 • Letter: S

Question

s-Last-Year-Review-Questions (1) Microsoft PowerPoint llA Text Direction Align Text 2Shape Outine StylesShape Effects Convert to SmartArt. | ??n { } ? -Arrange Quick Paragraph Drawing Membrane potential-4 In a cell at resting state, and relative ion permeability gra-1, g,-10. ?? is-80mV, EN, is +45mV, Ec is -80mV, and membrane potential Em is -64mV. In this cell, if Cl ion permeability becomes 10, how the membrane potential changes? A. hyperpolarized B. depolarized C. no change in the membrane potential D. equal to O mV E. repolarized

Explanation / Answer

The correct option is A. hyperpolarized.

Em = -64 mV, gK = 10, gNa = 1, gCl = 10, EK = -80 mV, ENa = +45 mV, ECl = -80 mV.

gtotal = gK + gNa + gCl = 10 + 1 + 10 = 21

Em = (gK EK + gNa ENa + gCl ECl)/gtotal = (10 x (-0.080) + 1 x 0.045 + 10 x (-80))/21 = -0.074 = -74 mV

Em has decreased from -64mV to -74 mV. Hence it gets hyperpolarized.