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A woman\'s father has ornithine transcarbamylase deficiency (OTD), an -linked re

ID: 23179 • Letter: A

Question

A woman's father has ornithine transcarbamylase deficiency (OTD), an -linked recessive disorder producing mental deterioration if not properly treated. The woman's mother is homozygous for the wild-type allele.

Part A
What is the woman's genotype?

Part B
If the woman has a son with a normal man, what is the chance the son will have OTD?
If the woman has a son with a normal man, what is the chance the son will have OTD?
0%
25%
50%
75%
100
Part C
If the woman has a daughter with a man who does not have OTD, what is the chance the daughter will be a heterozygous carrier of OTD? What is the chance the daughter will have OTD?



100% chance to be heterozygous carrier of OTD, 0% chance to have OTD.
50% chance to be heterozygous carrier of OTD, 0% chance to have OTD.
50% chance to be heterozygous carrier of OTD, 25% chance to have OTD.
100% chance to be heterozygous carrier of OTD, 50% chance to have OTD.
50% chance to be heterozygous carrier of OTD, 50% chance to have OTD.
Part D
Identify a male with whom the woman could produce a daughter with OTD.


dY
DY
Dd
dd

Part E
For the instance you identified in part (d), what proportion of daughters produced by the woman and the man are expected to have OTD?

25%
100%
50%
75%
Part F
For the instance you identified in part (d), what proportion of sons of the woman and the man are expected to have OTD?
75%
25%
100%
50%




Explanation / Answer

part a:x^ox part b:100% part c:0%and100% part d:DY part e:100% part f:100%

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