Research Method A case-control study examined the effect of prescription antibio

Question

Research Method

A case-control study examined the effect of prescription antibiotic use during pregnancy on childhood cancer. Cases were randomly chosen from children with cancer in a cancer registry in the United States, and controls were selected randomly from the United States population. Exposure to prescription antibiotics during pregnancy was determined from interviews given to the child’s mother. The study reported an odds ratio of 2.1, and suggested that there was a causal relation between antibiotics and childhood cancer. Give an alternative explanation for these findings. please explian in detials ???

Explanation / Answer

Since this is a case-control study in which A we examined the effect of prescription antibiotic use during pregnancy on childhood cancer the odds ratio of 2.1 is subject to selection bias Information on exposure is subject to observation bias. Hence such studies do not allow the calculation of incidence for finding the absolute risk. Various other factors such as; genetic and environmental may have led to this observation.

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