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35. Which of the following thrombolytics is the only agent in the class with an

ID: 240618 • Letter: 3

Question


35. Which of the following thrombolytics is the only agent in the class with an FDA approved indication for treating an acute ischemic stroke?

a. Alteplase

b. Reteplase

c. Streptokinase

d. Tenecteplase


36. A patient with an ST-elevation myocardial infarction (STEMI) who is at low risk for mortality and elevated risk for an intracranial hemorrhage would benefit most from which of the following thrombolytic agents?

a. Alteplase

b. Reteplase

c. Streptokinase

d. Tenecteplase


37. In a patient with an acute ischemic stroke, which of the following blood pressures represents the threshold, above which must be treated before the initiation of a thrombolytic?

a. 140/90 mmHg

b. 160/100 mmHg

c. 185/110 mmHg

d. 210/115 mmHg


38. Which of the following populations represents the most appropriate patients to receive thrombolysis to treat a pulmonary embolism?

a. Acute massive pulmonary embolism with blood pressure of 80/60 mmHg

b. Acute massive pulmonary embolism with blood pressure of 180/100 mmHg

c. Submassive pulmonary embolism with blood pressure of 80/60 mmHg

d. Submassive pulmonary embolism with blood pressure of 180/100 mmHg


39. Concomitant use with which of the following agents would contraindicate the use of a thrombolytic?

a. Aspirin

b. Celecoxib

c. Clopidogrel

d. Rivaroxaban


40. A patient who received alteplase for treatment of an acute pulmonary embolism is experiencing black, tarry stools. Which of the following parameters should be closely monitored?

a. Blood pressure

b. Hemoglobin

c. International normalized ratio (INR)

d. Prothrombin time

Explanation / Answer

35. ANSWER A

alteplase is the only US Food and Drug Administration (FDA)-approved medical therapy for treatment of patients with acute ischemic stroke.

36. Answer is C Streptokinase
37. Answer is C
185/110 mmHg

38. answer D

39. Anwer A

40.Answer A

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