Written Assignments L. Briefly describe the biogenic amine theory of depressin H
ID: 247998 • Letter: W
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Written Assignments L. Briefly describe the biogenic amine theory of depressin How does current drug therapy to treat depression correlate with the biogenic amine theory? 2. Discuss specific nursing considerations related to the use of antidepressants in children, adults, and older adults. 3. An increased risk of suicide has been reported with the initiation of antidepressant therapy. Describe nursing assessment and nursing considerations related to suicidal ideation. Group Assignments 1. Each group constructs a table that summarizes the therapeutic actions, indications, pharmacokinetics, contraindications, common adverse reactions, and important drug-drug interactions with each class of antidepressants: tricyclic antidepressants (TCA), monoamine oxidase (MAO) inhibitors, selective serotonin reuptake inhibitors (SSRI), and miscellaneous agents. 2. Assign each group one class of antidepressants. The group compares the prototype drug to the drugs in the classi ficationExplanation / Answer
1.Biogenic Amine Hypothesis which postulates that a number of depression result from a deficiency or excess in biogenic amines (e.g. norepinephrine). Thus, the solution is to check for abnormalities in the production, secretion, and metabolism of these amines. Hypothesis supports the theory that there are certain mental and psychological disorders which originate from an imbalance in biogenic amines.
Antidepressants are used for therapy. Including SSRIs fluoxetine (Prozac), sertraline (Zoloft), paroxetine (Paxil) citalopram (Celexa), escitalopram (Lexapro), fluvoxamine (Luvox)and related types (selective noradrenaline reuptake inhibitors – SNRIs – and noradrenaline reuptake inhibitors – NARIs) are better tolerated and safer than either tri-cyclics or MAOIs, Phenelzine (Nardil).
2. Fluoxetine can be helpful in treating childhood depression, and can lead to significant improvement of depression overall. For adults and older adult treatments include antidepressant medications, cognitive behavioral therapy- CBT or both.
3. SSRI antidepressant medications have fewer side effects and are less likely to be harmful if taken in an overdose, which is an issue for patients with depression already at risk for suicide. So psychotherapies included "cognitive behavioral therapy," which helps people learn new ways of thinking and behaving, and "interpersonal therapy," which helps people understand and work through troubled personal relationships.
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