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Comparison screening test for skin cancer with biopsy findings of 1,000 consecut

ID: 248526 • Letter: C

Question

Comparison screening test for skin cancer with biopsy findings of 1,000 consecutive patients who underwent biopsy Biopsy Total Screening Test Skin cancer No skin cancer Total Skin cancer 90 10 100 No skin cancer 180 720 900 270 730 1,000 Using the data in the table above if you were to use the same screening criteria (Sensitivity and Specificity) to screen persons in a population with a prevalence estimate consequence of using the screening test for skin cancer in this population? d at 5 per 1,000 patients, which of the following is a lik Most screening positive for skin cancer will be false positives. Since the sensitivity and specificity are the same the results will remain the same. O Most of the screening positive for skin cancer will be true skin cancer. O Most screening positive for skin cancer will be false negatives.

Explanation / Answer

Most screening positive for skin cancer will be false positives..
five recent prospective studies of the accuracy of skin examination in screening programs independently calculated these values sensitivity as the number of melanomas that were true positive..divided by the total number of melanomas true positive and true negatives..In the biopsy studies among patients with suspected melanomas 100 people with positive results and 900 people with negative results that is nonmelanomas..So most screening positive test people with skin lesions under biopsy test and according to the sensitivity and specificity it shows false positive results.

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