Part lll - Regulation Questions 3. Blood pH is normally regulated by the respira

Question

Part lll - Regulation Questions 3. Blood pH is normally regulated by the respiratory system to control the level of CO, (2) and by the urinary system to control the levels of HCO, and non-volatile acids in the blood. Metabolism CO2 Tissue Tubular lumen Proximal renal Tubular cell Capillary endothelium CO Carbonic anhydrase Carbonic anhydrase Blood Plasma HC Alveolus (in lungs) CO2+ H20 Na Carbonic anhydrase H+ + HCO3. HCO3. CI RBC Given the overall reaction, CO2 (g) + H2O (!) ?,??, (aq) Ekco, (aq) + H* (aq), what effect would each of the following have on blood pH? Explain with LeChatlier's principle. a. Hyperventilating b. Holding your breath for an extended period of time c. Excessive ingestion of baking soda, HCO d. Inhibiting renal carbonic anhydrase 4. Mary has an acid-base disturbance that is being compensated for with another body system. Identify the ype of disturbance and trace out the physiological pathway responsible for the compensating action. L41 5. For each of the treatments listed below, indicate whether you would recommend it (yes) or not (no) to correct Mary's problem? Explain what effect each treatment would have upon her blood pH. a. Breathing in a paper bag b. An IV containing pure HCO, in an isotonic solution c. Holding her breath for as long as she can d. An IV containing pure CO,2 in an isotonic solution

Explanation / Answer

Le Chatelier's Principle

If a dynamic equilibrium is disturbed by changing the conditions, the position of equilibrium moves to counteract the change.

3.

a. Hyperventilation causes a decrease of carbon dioxide in the body and causing the pH of the blood to increase and become more alkaline. Thus compensating the metabolic acidosis.

b. Holding the breath causes increased levels of CO2 in the blood and it combines with water to form Carbonic Acid (H2CO3). Which in turn dissociates into a bicarbonate ion and H+ ion.
c. Baking soda-induced severe metabolic alkalosis as it dissociates into sodium and HCO3

d. A carbonic anhydrase inhibitor the reduces formation of hydrogen and bicarbonate ions from carbon dioxide and water. Thus it causes sodium bicarbonate diuresis and a reduction in total body bicarbonate stores.

4. Patient’s blood pH is 7.31 and it suggests a metabolic acidosis with HCO3 – of 8.9, a condition called primary bicarbonate deficiency.

The metabolic acidosis is compensated by the respiratory system Due to the decreased blood pH and HCO3-, as the lab values suggest. The PCO2 levels are 18.1 mmHg (<35mmHg).

5. a. breathing into paper bag fill it with carbon dioxide and breathe the exhaled air from the bag back into the lungs.

Doing this several times can improve the body the carbon dioxide levels to normal.

b. The patient is not in need of IV HCO3 now. If the condition further deteriorates (pH <7.21, PCO2 <15mmHg) , IV compensation can be done.

c. Yes,

d. No

Related Questions

Navigate

• Browse (All)
• Browse P
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.