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2. Investigators perform an experiment to examine the time-dependent processes o

ID: 252368 • Letter: 2

Question

2. Investigators perform an experiment to examine the time-dependent processes of memory formation. Specifically, rats are trained using the inhibitory avoidance paradigm and then treated with an amnesia-inducing drug 1, 2, or 12 hours later. The retention latency of the rats is tested 48 hours after training. They find that rats receiving the drug 1 or 2 hours after training have no memory for the task when test at 48 hrs, whereas those receiving the drug 12 hours after training have maximum retention latencies. They publish a paper arguing that memory consolidation for inhibitory avoidance learning in rats takes between 2 and 12 hours. .Do you agree with the conclusions made by the investigators? Why or why not? . What additional research would you want to see before accepting their conclusion? Or is there no additional research that would convince you. If so, give specific examples of results that they might generate that would still not convince you

Explanation / Answer

I agree with the conclusions because the memory needs long term consolidation rather than short term. We should not expect immediate response from the rat or any model organism as it takes some time to get acquainted with the conditions and moreover I would recommend testing on other model organisms too as it may helpful to gain conclusions.

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