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What is most notable about people who have 5-alpha reductase deficiency disorder

ID: 252737 • Letter: W

Question

What is most notable about people who have 5-alpha reductase deficiency disorder? Select one: a. They are born with intersex genitalia and identify as non-gendered, even as children b. They are born with a clitoris and labia but develop a penis at puberty and often develop a male gender identity c. They are born with penis and scrotum but develop a clitoris and labia genitalia at puberty and a female gender identity d. They are born with ovotestes and develop a male gender identity at puberty A chromosomally XX fetus develops fully functioning ovaries but also has CAH. How will the genitalia of this fetus likely develop? Select one: a. It will likely develop a clitoris and labia that are not masculinized in any way b. It will develop intersex genitalia c. It will develop a clitoris, penis, labia and scrotum d. No genitalia will develop

Explanation / Answer

Answer 1 a) They are born with intersex genitalia and identify as non-gendered, even as children.

Reason-  5-alpha reductase deficiency predominantly affects male development. such embryos have a very low level of hormone dihydrotestosterone. and such children are often born as having intersex genitalia due to which their gender is not clearly identified and they are raised as either nonidentified or misidentified gender.

Answer 2 a)  It will likely develop a clitori and labia that are not masculinized in any way.

Reason- As this XX female has a fully functioning ovary so she must follow a development of clitori and labia. but due to congenital adrenal hyperplasia, deficiency of 21-hydroxylase will result in poor masculinization of her genitalia.

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