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plied Questions or each of the diseases described in situations a through indica

ID: 253094 • Letter: P

Question

plied Questions or each of the diseases described in situations a through indicate which of the following phenomena (A-H) is at work. More than one may apply. A. lethal alleles B. multiple alleles C. epistasis D. incomplete penetrance E. variable expressivity F. pleiotropy G. a phenocopy H. genetic heterogeneity a. A woman with severe neurofibromatosis type 1 has brown spots on her skin and several large tumors beneath her skin. A genetic test shows that her son has the disease-causing autosomal dominant allele, but he has no symptoms. b. A man would have a widow's peak, if he wasn't bald. c. A man and woman have six children. They also had two stillbirths-fetuses that died shortly before birth. d. Mutations in a gene that encodes a muscle protein called titin cause 22 percent of cases of inherited dilated cardiomyopathy, a form of heart disease. Other single genes cause the remaining cases e. A woman with dark brown skin uses a bleaching cream with a chemical that darkens her fingertips and ears, just like the inherited disease alkaptonuria. r ntrievrers, the B allele confers black coat ene

Explanation / Answer

A- option c

B-option a

C-option f

D-option e

E-option d

F-option h

G-option i

H-option g