A Family In Need: Internet-Enhanced Case Study on Cancer Genetics s by Janet A.

Question

A Family In Need: Internet-Enhanced Case Study on Cancer Genetics s by Janet A. De Souza-Hart School of Arts & Sciences Massachusetts College of Pharmacy & Health Sciences, Boston, MA Instructions: Using the information that you have learned in class and from your textbook, complete the questions in the case. Internet sites and resources are cited below in the case study for you to use to look up key information. Partl- Genetic Testing You are a second-year medical student in an innovative medical school that allows you to get in-depth dinical experience early in your medical education. You are currendly assigned to work with Dr. Aikenhed, a pediatric oncologist. She has done a biopsy on a tumor-like growth in the adrenal gland of her 17-year-old patient, Lee E You record the following notes while Dr. Aikenhed takes a detailed family history from the patient's parents: cation. You are currently assigned to work with De. .Lee has a sister, Leah (age 10), and a brother, Luke (age 6). Both are healthy. Lee's mother, Grace, was diagnosed with bilateral breast cancer last year at age 35. Lee's father, Brian, and Lee's patemal grandparents have no history of cancer. is the youngest of four children. Her eldest brother, Greg (age 42), and sister, Greta (age 40), have never had any signs or symptoms of cancer. She had a beother, Geoff, who died of leukemia at age 8. He was the third child of Grace's parents, .Greg's two fraternal twin daughters have no signs or symptoms of cancer. Grace's father, Roger, died of a soft tissue sarcoma at age 35. Graces mother, Renee, is sll living and in excellent health .Rogers mother died of a brain tumor at age 30. Roger was her only child.

Explanation / Answer

1. She is concerned because they might end up having that cancer later

2. We acquire genes from both our parents. If a parent has a gene defect then each child has a 50% of acquiring it. when one is born with an inherited defective gene it doesn't mean that a person will unquestionably get cancer. they just have a greater chance of acquiring selective types of cancer than others.

Now, All cancers are induced by genetic mutations, but not all genetic mutations are inherited. So, if a persons' parents do not have faulty genes they can still have cancer due to mutation.

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