Question 1 (1 point) Which of the following events occur in the pathway in which

Question

Question 1 (1 point) Which of the following events occur in the pathway in which sperm-specific phospholipase C (PLC) stimulates the egg of a starfish to block polyspermy and initiate embryonic development after the sperm fuses with the egg plasma membrane during fertilization? (Select ALL that are TRUE) a) Ca+ released from the ER activates a trimeric G protein, causing release of GDP from the alpha subunit of the G protein. 0 b) PLC cleaves an inositol phospholipid into diacylglycerol and inositol (phosphorylated sugar IP3) c) The phosphorylated sugar IP3 diffuses to the ER, where it acts as a ligand to open a ligand- ated Ca channel in the ER membrane. d) Protein kinase C (PKC) binds to diacylglycerol in the plasma membrane. e) Protein kinase C is activated by an inward Na current in the plasma membrane.

Explanation / Answer

C) The phosphorylated sugar IP3 diffuses to the ER where it acts as a ligand to open a ligand gated Ca+2 channel in the ER membrane.

At the time of fertilisation the sperm initiates the rise in calcium levels in the egg in response to innositol tri phosphate rise.

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