odel 3 - Pedigree of Hemophilia in a Royal Family Beatnce Henry 2 Alfonso XillEu

Question

odel 3 - Pedigree of Hemophilia in a Royal Family Beatnce Henry 2 Alfonso XillEugenie Leopold Maurice of Spain 3 Alfonso Gonzalo ? JC Hint Juan Carlos of Spain 17. Identify the gender and phenotypes of Beatrice and Henry's children. * Eugenie's phenotype: XHXn, carrier but normal pheno x Leopoid's phenotyee- XhY-hemophilia, Male yMaurice's phenatype- XhY - hemophilia. Male 18. Beatrice's daughter, Eugenie, married Alfonso XIlI of Spain. Identify the gender ane children. Aons o 's pheno ype - XhÝ-hemophilia, Male Genzalo s phunotye XhY -hemoph lio, Male

Explanation / Answer

According to the pedigree given in Model 3 and the paragraph given in Read this, Haemophillia is a X-linked receccive disease. The genes associated with these conditions are located on the X chromosome, which is one of the two sex chromosomes.In males (who have only one X chromosome), one altered copy of the gene in each cell is sufficient to cause the condition. In females (who have two X chromosomes), a mutation would have to occur in both copies of the gene to cause the disorder. Because it is unlikely that females will have two altered copies of this gene, it is very rare for females to have hemophilia. A characteristic of X-linked inheritance is that fathers cannot pass X-linked traits to their sons which is evident from the pedigree chart given in the question.

Related Questions

Navigate

• Browse (All)
• Browse O
• Subjects

---

---

Integrity-first tutoring: explanations and feedback only — we do not complete graded work. Learn more.