Following is a picture of the 3-D structure of globular protein the fragmenta wi

Question

Following is a picture of the 3-D structure of globular protein the fragmenta with well- defined secondary structure are labelled with letters I1. A. Please find and label the N terminal of the protein B. The fragment(s) that fold(s) into an ? helix- - -- -- - C. The fragment(s) that fold(s) into a ?-sheet- D. The fragment(s) that fold(s) into a parallel ?-sheet. E. The fragment(s) that fold(s) into an anti-parallel ?-sheet The major noncovalent interaction that make the fragment B and C associated to each other is F.

Explanation / Answer

Answer:

II. (A) The starting end of the beta sheet labelled "C" is the N-terminal of the protein

(B) "A" folds into alpha helix

(C) B, C, D and F folds into beta sheet

(D) C and D form parallel beta sheets

(E) B-C and D-F forms antiparallel beta sheets

(F) Hydrogen bond forms the major interaction. Hydrogen bonding between the two antiparallel strands holds the two strands togather.

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