41. Acety Figure below. Which of the following would decrease this effect of the

Question

41. Acety Figure below. Which of the following would decrease this effect of the acetylcholine? Icholine binds to a GPCR on heart muscle, making the stimulates a G protein, which heart beat more slowly. The activated opens a K+ channel in the plasma membrane, as shown in the EXTRACELLULAR SPACE 1 GPROTEIN G proteln A) addition of a high concentration of GTP 8) addition of a drug that promotes the a subunit to exchange GDP for GTP C) addition of a drug that reduces the a subunit to exchange GDP for GTP D) mutations in the acetylcholine receptor that increase its interaction with the G protein 42. Which of the following statements is true? A) MAP kinase is important for phosphorylating MAP kinase kinase. B) PI 3-kinase phosphorylates PIP2 to generate PIP3 in the plasma membrane to promote cell survival. C) Ras becomes activated when an RTK directly promotes Ras to exchange its bound GDP for GTFP D) STAT proteins phosphorylate JAK proteins, which then enter the nucleus and activate gene transcription 43. Adenylyl cyclase stimulation takes place after receptors bind hormone because A) of the generation of GTP-bound a subunit of G protein. B) of the generation of GDP-bound a subunit of G protein. C) adenylyl cyclase binds to receptor D) the G protein subunit converts ATP to CAMP 44. Activation of skeletal muscle phosphorylase kinase is most likely due to A) parathyroid hormone receptor activation, which results in increased levels of calcium in the blood. B) insulin receptor activation, which results in increased levels of sugar in the blood. C) adrenaline binding of cell receptors, leading to increased blood levels of glucose. D) glucocortioid binding of cell receptors, leading to decreased blood levels of glucose. 45. Increased production of IP3 in muscle cells of the gastrointestinal tract can leads to A) excess levels of cAMP B) inactivation of thick filament ATPase subunits C) increased levels of calcium within the cytosol of smooth muscle cells D) increased levels of calmodulin within the cytosol of smooth muscle cells

Explanation / Answer

Ans-41. B (because GTP is necessory to activate G protein)

Ans-42. D ( JAK phosphorylate STAT protein and STAT enter into the nucleus . Not JAK )

Ans-43. A

Ans-44. A

Ans-45. C ( beacuse it cause opening of ip3 induced ca+ channel)

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