Which of the following are true in regard to Ca2+ in the cell? A. The large grad

Question

Which of the following are true in regard to Ca2+ in the cell?

A. The large gradient tending to drive Ca2+ into the cytosol from both the ER and plasma membranes leads to Ca2+ rushing into the cytosol when Ca2+ channels are activated.

B. The frequency of Ca2+ oscillation can code a specific cellular response.

C. Ca2+ directly activates PKA by releasing it from inhibitory subunits

D. Increased local Ca2+ opens nearby IP3 and Ryanodine receptors by calcium-induced calcium release.

E. Calcium ATPases in the plasma membrane and ER help to maintain low levels of calcium in the cytosol.

Explanation / Answer

Ans. E

(( two type of ATPase, in plasma membrane(PMCA) and in SER i.e (SERCA) they store back the calcium after muscles has contracted or when not further need of more calcium ))

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