Can you explain or show as simply as possible how each of these solved answers w

Question

Can you explain or show as simply as possible how each of these solved answers were obtained?

Dilated cardiomyopathy (DCM) in dogs occurs because of abnormal enlargement of the chambers of the heart with simultaneous reduction in cardiac output. The left ventricle is always involved, but in advanced cases, dilation of all four chambers might be involved. Genetically, dogs inherit DCM as an autosomal dominant disorder. However, dogs heterozygous for the DCM allele do not always express the disorder a. Provide the terminology that best describes why this disorder may not be expressed in all dogs that are heterozygous for the DCM allele. b. In some dogs, when the DCM allele is present, DCM may manifest as a mild disorder, whereas, in some other dogs DCM may appear quite severe. What terminology might you use to describe this type of gene expression patterm? ?1n guinea pigs, coat color can be white, cream or yellow. Of these three phenotypes, only the cream-colored guinea pigs never breed true. When two cream-colored guinea pigs are crossed, are yellow, V% are cream and 4 are white. A cream-colored guinea pig by white guinea cross yields V4 cream and white offspring. a. How many genes control coat color in the guinea pig?n b. Give the mode of inheritance of coat color in the guinea pig wh'k c. Why is it impossible for cream-colored guinea pigs to breed true? 10. In Humans, Hemochromatosis (excessive iron in the blood) is a dominant disorder showing 33 % penetrance. A person who is heterozygous for Hemochromatosis mates with a person who is also heterozygous for hemochromatosis. Hint: Do not disregard any information given in the scenario above. What is the probability that the couple will have 2 children with Hemochromatosis ? What is the probability that the couple will have a child with Hemochromatosis or a child without hemochromatosis? a. b.

Explanation / Answer

(9)

(a)two genes control coat color in guinea pigs

ww=white

yy=yellow

wy=cream

(b)Incomplete dominance

Under homozygous condition they are true breeding but under heterozygous condition they are cream colored

(c) Thats because the genes w and Y segregate during inheritance.

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