This is a fill in the blank The vast number of different antibody molecules that

Question

This is a fill in the blank

The vast number of different antibody molecules that is made by a single human being is achieved by [a] association of multiple [b] segments termed V ([c]) and J ([d]), which together encode the [e] region of the [f] chain of an immunoglobulin molecule; the V, D ([g]), and J, encode the [h] region of the [i] chain of an immunoglobulin molecule.

The vast number of different antibody molecules that is made by a single human being is achieved by [a] association of multiple [b] segments termed V ([c]) and J ([d]), which together encode the [e] region of the [f] chain of an immunoglobulin molecule; the V, D ([g]), and J, encode the [h] region of the [i] chain of an immunoglobulin molecule.

Explanation / Answer

The vast number of different antibody molecules that is made by a single human being is achieved by:association of multiple segments termed V and J which together encode the region of the chain of an immunoglobulin molecule; the V, D and J, encode the region of the chain of an immunoglobulin molecule.

The diversity of antibody occur in following steps:

Antibody Genes Are Assembled From Separate Gene Segments During B Cell Development,

each Variable Region Is Encoded by More Than One Gene Segment.

Imprecise Joining of Gene Segments Greatly Increases the Diversity of V Regions.

Antigen-Driven Somatic Hypermutation Fine-Tunes Antibody Responses

The Control of V(D)J Joining Ensures That B Cells Are Monospecific

When Activated by Antigen, a B Cell Switches From Making a Membrane-Bound Antibody to Making a Secreted Form of the Same Antibody

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