Observation: Transcription Unwind your DNA model so that only one strand remains
ID: 257816 • Letter: O
Question
Observation: Transcription Unwind your DNA model so that only one strand remains. This strand is the sense strand, the strand that is transcribed. Assume that the sense strand has the sequence of bases shown in Table 10.2. Complete Table 10.2 to show the sequence of bases in mRNA. 1. Table 10.2 Transcription mRNA Why are the bases in Table 10.2 shown in groups of three? Every three bases in mRNA is called a 2. 3. Translation Translation takes place in the cytoplasm. During translation, the sequence of mRNA codons determines the sequence of amino acids in a polypeptide. Small molecules of transfer RNA (IRNA) are located in the cytoplasm. At one end, a tRNA bears a particular amino acid, and at the other end, it has a certain anticodon, three bases that are complementary to an mRNA codon. As before, A pairs with U, and C pairs with G (see Table 10.1). As ribosomes containing ribosomal RNA (rRNA) pass along the mRNA RNA anticodons pair with mRNA codons by complementary base pairing (Fig. 10.4). The order in which the tRNA molecules line up determines the o polypeptide. Polypeptide formation is called translation translated into a sequ amino acids. (A protein contains one or more polypeptides.) because an mRNA nucleotide sequence is ence of amino acids. Polypeptides differ from one another by the sequence of theirExplanation / Answer
DNA sense strand : TAC GGG CTA CAA CTT AAC AGA CCA ATC
Transcribed mRNA strand: AUG CCC GAU GAA UUG UCU GGU UAG
2) The bases are shown in groups of three to make it convinient for the reader to determine the reading frame of the gene as the genetic codons are triplet in nature and are read in groups of three.
3) Every three bases in mRNA is called as genetic codon. Each genetic codon codes for a specicific amino acid and is universal in nature across all species with a few notable exceptions. During translation, the sequence of mRNA codons determine the sequence of amino acids in a polypeptide.
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