1 a) Which of the following consequences of a signaling molecule binding to its

ID: 258027 • Letter: 1

Question

1 a) Which of the following consequences of a signaling molecule binding to its receptor is NOT a short-term response?

cAMP binding and protein activation

ubiquitination of a target protein, resulting in its degradation

chromatin remodeling, resulting in transcriptional changes

phosphorylation by a kinase

1 B) Which of the following does NOT correctly identify the type of signaling described?

insulin secreted by the pancreas – endocrine

interleukin-1 production by monocytes in response to external stimuli and binding to receptors on the same cell – autocrine

release of growth factors from cells to target adjacent cells – paracrine

the release of neurotransmitters by neurons at a synapse – endocrine

1.A

cAMP binding is the long term effect as it transduces broad variety of signals in different types of cells. Hence, option A is correct.

1. B.

The release of neurotransmitters by neurons at a synapse is stimulated by stimulus. Hence, option D is incorrect.

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